Prion protein

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Prion Diseases and Their Biochemical Mechanisms - NCBI - NIHPrion diseases, also known as the transmissible spongiform ... Within the context of the 'protein-only' model, prion strains are believed to be ... Millhauser GL.A Structural Overview of the Vertebrate Prion Proteins - NCBI - NIHKey Words: amyloid, NMR, prion, scrapie, structure, X-ray ... PrP diseases are thought to be part of the larger family of pathologies which is ... Millhauser GL.Conformational conversion of prion protein in prion diseases | Acta ...2013年4月11日 · Cellular prion protein is a soluble monomeric protein that is readily degradable by proteinase K. In contrast, scrapie prion protein (PrPSc) forms ...The biological function of the cellular prion protein: an update | BMC ...2017年5月2日 · The misfolding of the cellular prion protein (PrPC) causes fatal ... Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, et al.Copper Binding in the Prion Protein | Accounts of Chemical Research2004年1月23日 · A conformational change of the prion protein is responsible for a ... W. G.; Millhauser, G. L. Molecular features of the copper binding sites in the ...The prion protein is embedded in a molecular environment that ...2018年6月5日 · Here, we interrogated the interactome of the prion protein (PrP), best known for ... The study uncovered 26 proteins that reside in proximity to PrP. ... Research articles · Collections · Subjects · Follow us on Facebook · Follow us on Twitter ... Dr. Charles Weissmann (The Scripps Research Institute, Jupiter, FL, ...Early Onset Prion Disease from Octarepeat Expansion Correlates ...2009年4月17日 · An unusual class of inherited mutations giving rise to prion disease involves ... Millhauser GL (2004) Copper binding in the prion protein.Host prion protein expression levels impact prion tropism for the ...2020年7月23日 · PrPC expression levels may thus be instrumental in prion tropism for the lymphoid tissue. From a diagnostic point of view, given the apparent complexity of prion diseases with respect to prion ... Sum of Facebook and Twitter activity. ... Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, ...Characterization of prion protein function by focal neurite stimulation ...The cellular prion protein (PrPC), encoded by the PRNP gene, is a ubiquitous glycoprotein, which is highly ... L.A., D.C. and G.L. designed the experiments.[PDF] N-Terminal Regions of Prion Protein: Functions and Roles in ... - MDPI2020年8月28日 · Abstract: The normal cellular isoform of prion protein, designated PrPC, ... Keywords: prion protein; prion; prion disease; neurodegeneration; protein ... Hutter, G.; Heppner, F.L.; Aguzzi, A. No superoxide dismutase activity of ...